This is a list of the current House seats and the incumbents occupying them. All 435 of these seats are up for election on 8 November 2022.

There has been 3 deaths, 9 resignations, and 0 changes of party affiliation in the 117^th House.

• Member of Congress-elect Luke Joshua Letlow (Republican, Louisiana, CD 5) died on 29 December 2020.
• Member of Congress Cedric L. Richmond (Democratic, Louisiana, CD 2) resigned effective 15 January 2021 to become Senior Adviser to the President and White House Public Engagement Director in the Biden Administration.
• Member of Congress Ron Wright (Republican, Texas, CD 5) died on 7 February 2021.
• Member of Congress Claudia Tenney (Republican, New York, CD 22) was sworn on 11 February 2021 after a contested 3 November 2020 election.
• Member of Congress Marcia L. Fudge (Democratic, Ohio, CD 11) resigned on 10 March 2021 to become Secretary of Housing and Urban Development in the Biden Administration.
• Member of Congress Debra A. "Deb" Haaland (Democratic, New Mexico, CD 1) resigned on 16 March 2021 to become Secretary of the Interior in the Biden Administration.
• Member of Congress Julia Letlow (Republican, Louisiana, CD 5) was elected in a Special Election on 20 March 2021 and sworn on 14 April 2021.
• Member of Congress of Alcee L. Hastings (Democratic, Florida, CD 20) died on 6 April 2021.
• Member of Congress of Steve E. Stivers (Republican, Ohio, CD 15) announced his resignation on 19 April 2021, effective 16 May, to take a position with the Ohio Chamber of Commerce.
• Member of Congress Troy Carter (Democratic, Louisiana, CD 2) was elected in a Special Election on 24 April 2021 and sworn on 11 May 2021.
• Member of Congress Melanie Ann Stansbury (Democratic, New Mexico, CD 1) was elected in a Special Election on 1 June 2021 and sworn on 14 June 2021.
• Member of Congress John Kevin "Jake" Ellzey, Sr. (Republican, Texas, CD 6) was elected in a Special Election on 27 July 2021 and sworn on 30 July 2021.
• Member of Congress Shontel M. Brown (Democratic, Ohio, CD 11) was elected in a Special Election on 2 November 2021 and sworn on 4 November 2021.
• Member of Congress Mike Carey (Republican, Ohio, CD 15) was elected in a Special Election on 2 November 2021 and sworn on 4 November 2021.
• Member of Congress of Devin Gerald Nunes (Republican, California, CD 22) announced his resignation on 6 December 2021 and formally resigned on 3 January 2022. He will become CEO of Trump Media & Technology Group.
• Member of Congress Sheila Cherfilus-McCormick Democratic, Florida, CD 20) was elected in a Special Election on 11 January 2022 and sworn on 18 January 2022.
• Member of Congress of Jeffrey Lane "Jeff" Fortenberry (Republican, Nebraska, CD 1) announced his resignation on 24 March 2022 effective 31 March 2022. He was convicted of felony concealing conduit campaign contributions (1 count) and making false statements to federal agents (2 counts) on 24 March 2022.
• Member of Congress of Filemon B. Vela (Democratic, Texas CD 34) resigned on 31 March 2022. Earlier, he announced he was going to take a position at the Akin Gump, a law firm.
• Member of Congress of Antonio Delgado (Democratic, New York CD 19) was designated as the new Lieutenant Governor by New York Governor Kathleen Courtney "Kathy" Hochul (Democratic) on 3 May 2022 and resigned from Congress on 25 May 2022.
• Member of Congress of Thomas W. "Tom" Reed, II (Republican, New York CD 23) resigned on 10 May 2022. He had previously announced that he would not run for re-election due to alcohol dependence and allegations of sexually harassment.